TBL1XR1 anticorps

N° du produit ABIN6567965

L’anticorps Lapin Polyclonal anti-TBL1XR1 a été validé pour WB et IF. Il convient pour détecter TBL1XR1 dans des échantillons de Humain et Souris.

Aperçu rapide pour TBL1XR1 anticorps (ABIN6567965)

Antigène: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBL1XR1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-TBL1XR1 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human TBL1XR1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TBL1XR1

Antigène: TBL1XR1 (Transducin (Beta)-Like 1 X-Linked Receptor 1 (TBL1XR1))

Autre désignation: TBL1XR1

Sujet:

Synonyms: C21,DC42,F box like/WD repeat containing protein TBL1XR1,F-box-like/WD repeat-containing protein TBL1XR1,FLJ12894,IRA1,Nuclear receptor corepressor/HDAC3 complex subunit,Nuclear receptor corepressor/HDAC3 complex subunit TBLR1,TBL1 related protein 1,TBL1-related protein 1,TBL1R,TBL1XR1,Transducin (beta) like 1 X linked receptor 1,Transducin beta like 1X related protein 1,Transducin beta-like 1X-related protein 1

Background: This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.

Poids moléculaire:

Observed_MW: 55-70kDa

Calculated_MW: 55kDa

ID gène: 79718

UniProt: Q9BZK7

Pathways: Regulation of Lipid Metabolism by PPARalpha